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Key Publications

  1. Best practice recommendations for the diagnosis and management of hypoparathyroidism. Khan AA, Ali DS, Bilezikian JP, et al. Best practice recommendations for the diagnosis and management of hypoparathyroidism. Metabolism. 2025;171:156335. doi:10.1016/j.metabol.2025.156335

  2. Hypoparathyroidism: diagnosis, management and emerging therapies. Khan S, Khan AA. Hypoparathyroidism: diagnosis, management and emerging therapies. Nat Rev Endocrinol. 2025 Jun;21(6):360-374. doi: 10.1038/s41574-024-01075-8. Epub 2025 Feb 4. PMID: 39905273.

  3. Guideline No. 422g: Menopause and Osteoporosis. Khan AA, Alrob HA, Ali DS, Dandurand K, Wolfman W, Fortier M. Guideline No. 422g: Menopause and Osteoporosis. J Obstet Gynaecol Can. 2022 May;44(5):527-536.e5. doi: 10.1016/j.jogc.2021.09.013. PMID: 35577424.
  4. Hypercalcemia in Pregnancy. Dandurand K, Ali DS, Khan AA. Hypercalcemia in Pregnancy. Endocrinol Metab Clin North Am. 2021 Dec;50(4):753-768. doi: 10.1016/j.ecl.2021.07.009. PMID: 34774246.
  5. Canadian national hypoparathyroidism registry – an overview of hypoparathyroidism in Canada 
    Khan AA, AbuAlrob H, Punthakee Z, Shrayyef M, Werfalli RE, Kassem HA, Braga M, Millar A, Hussain S, Iqbal S, Khan T, Paul T, Van Uum S, Young JEM. Canadian national hypoparathyroidism registry: an overview of hypoparathyroidism in Canada. Endocrine. 2021 May;72(2):553-561. doi: 10.1007/s12020-021-02629-w
  6. PaTH Forward: a Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial of TransCon PTH in Adult Hypoparathyroidism. Khan AA, Rejnmark L, Rubin M, Schwarz P, Vokes T, Clarke B, Ahmed I, Hofbauer L, Marcocci C, Pagotto U, Palermo A, Eriksen E, Brod M, Markova D, Smith A, Pihl S, Mourya S, Karpf DB, Shu AD.  J Clin Med. 2021 Jun 30;10(13):2956. doi: 10.3390/jcm10132956.
  7. Primary Hyperparathyroidism in Pregnancy: Literature Review of the Diagnosis and Management. Ali, D.S.; Dandurand, K.; Khan, A.A. J. Clin. Med. 2021, 10, 2956. https://doi.org/10.3390/jcm10132956
  8. Management of Endocrine Disease: Hypoparathyroidism in pregnancy: review and evidence-based recommendations for management. Khan AA, Clarke B, Rejnmark L, Brandi ML European Journal of Endocrinology 2019 Feb 1;180(2):R37-R44. doi: 10.1530/EJE-18-0541.
  9. Standards of Care for Hypoparathyroidism in Adults. Khan AA, Koch C, Van Uum SHM, Baillargeon JP, Bollerslev J, Brandi ML, Marcocci C, Rejnmark L, Rizzoli R, Shrayyef MZ, Thakker RV, Yildiz BO, Clarke B. European Journal of Endocrinology (2019) 180, P1–P23
  10. Hypophosphatasia: Canadian Update on diagnosis and management. AA Khan, R. Josse, P. Kannu, J. Villeneuve, T. Paul, S.Van Uum, C.R. Greenberg Osteoporosis International March 2019 30:1713–1722
  11. Tools for Enhancement and Quality Improvement of Peer Assessment and Clinical Care in Endocrinology and Metabolism. by Aliya Khan, Anne Kenshole, Shereen Ezzat, Jeannette Goguen, Karen Gomez-Hernandez, Robert A. Hegele, Robyn Houlden, Tisha Joy, Erin Keely, Donald Killinger, André Lacroix, Sheila Laredo, Ally P.H. Prebtani, M. Z. Shrayyef, Chris Tran, Stan Van Uum, Rhoda Reardon, Antiope Papageorgiou, William Tays, and Merrill Edmonds Journal of Clinical Densitometry Sept 2017
  12. Case-Based Review of Osteonecrosis of the Jaw (ONJ) and Application of the International Recommendations for Management From the International Task Force on ONJ Aliya A. Khan, Archie Morrison, David L. Kendler, Rene Rizzoli, David A. Hanley, Dieter Felsenberg, Laurie K. McCauley, Felice O’Ryan, Ian R. Reid, Salvatore L. Ruggiero, Akira Taguchi, Sotirios Tetradis, Nelson B. Watts, Maria Luisa Brandi, Edmund Peters, Teresa Guise, Richard Eastell, Angela M. Cheung, Suzanne N. Morin, Basel Masri, Cyrus Cooper, Sarah L. Morgan, Barbara Obermayer-Pietsch, Bente L. Langdahl, Rana Al Dabagh, K. Shawn Davison, George K. Sándor, Robert G. Josse, Mohit Bhandari, Mohamed El Rabbany, Dominique D. Pierroz, Riad Sulimani, Deborah P. Saunders, Jacques P. Brown Juliet Compston on behalf of the International Task Force on Osteonecrosis of the Jaw Journal of Clinical Densitometry Jan 2017
  13. Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and International Consensus. Aliya A. Khan, David A. Hanley, Rene Rizzoli, Jens Bollerslev, J.E.M Young, Lars Rejnmark, Rajesh Thakker, Pierre D’Amour, Terri Paul, Stan Van Uum, M. Zakarea Shrayyef, David Goltzman, Stephanie Kaiser, Natalie E. Cusano, Roger Bouillon, Leif Mosekilde, Annie W. Kung, Sudhaker D. Rao, Sanjay K. Bhadada, Bart L. Clarke, Jian-min Liu, Quan-Yang Duh, E. Michael Lewiecki, Francisco Bandeira, Richard Eastell, Claudio Marcocci, Shonni J. Silverberg, Robert Udelsman, K. Shawn Davison, John T. Potts Jr, Maria Luisa Brandi, and John P. Bilezikian,  Osteoporos Int (2017) 28:1–19
  14. Management of Hypoparathyroidism: Summary Statement and Guidelines, Maria Luisa Brandi, John P. Bilezikian, Dolores Shoback, Roger Bouillon, Bart Clarke, Rajesh V. Thakker, Aliya Khan, and John T. Potts Jr, JCEM Epub 2016 Mar, DOI: 10.1210/jc.2015-3907
  15. Practice| Five things to know about Atypical Femoral Fractures Aliya Aziz Khan MD, Stephanie Kaiser MD CMAJ 2017 April 10;
  16. Atypical Femoral Fracture Alert Program, Aliya A. Khan, Sian Iles, Stephanie M. Kaiser, Linda Probyn, Angela Cheung, Steven Burrell, Canadian Association of Radiologists Journal 2016 Jun; 20:1-2. DOI:10.1016/j.carj.2016.04.002
  17. Cinacalcet normalizes serum calcium in a double-blind randomized, placebo-controlled study in patients with primary hyperparathyroidism with contraindications to surgery, Aliya Aziz Khan,John Bilezikian, Henry G Bone, Andrey Gurevich, Péter Lakatos, Waldemar Misiorowski, Liudmila Rozhinskaya, Marie-Louise Trotman and Miklos Toth, European Journal of Endocrinology 2015 May;172(5):527-35. doi: 10.1530/EJE-14-0877. Epub 2015 Jan 30
  18. Diagnosis and Management of Osteonecrosis of the Jaw: A Systematic Review and International Consensus, Khan A, Morrison A, Hanley D, Felsenberg D, McCauley L, O’Ryan F, Reid I, Rugglero S, Taguchi A, Tetradis S, Watts N, Brandi M, Peters E, Guise T, Eastell R, Cheung A, Morin S, Masri B, Cooper C, Morgan S, Obermayer-Pietsch B, Langdahl B, Al Dabagh R, Davison K, Kendler D, Sandor G, Josse R, Bhandari M, El Rabbamy M, Plerroz D, Sulimani R, Saunders D, Brown J, Compston J, J Bone Miner Res. 2015 Jan;30(1):3-23. doi: 10.1002/jbmr.2405
  19. A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of Alendronate on Bone Mineral Density and Bone Remodelling in Perimenopausal Women With Low Bone Mineral Density, Khan A, Fortier M, Menopause and Osteoporosis Working Group, Fortier M, Reid R, Abramson BL, Blake J, Desindes S, Dodin S, Graves L, Guthrie B, Johnston S, Khan A, Rowe T, Sodhi N, Wilks P, Wolfman N., J Obstet Gynaecol Can., 2014 Nov 36(11):976-982.
  20. Osteoporosis in Menopause, Khan A, Fortier M, Menopause and Osteoporosis Working Group, Fortier M, Reid R, Abramson BL, Blake J, Desindes S, Dodin S, Graves L, Guthrie B, Johnston S, Khan A, Rowe T, Sodhi N, Wilks P, Wolfman N., J Obstet Gynaecol Can. 2014 Sep;36(9):839-840.
  21. Atypical Femoral Fractures: A Teaching Perspective, Aliya A. Khan, William D. Leslie, Brian Lentle, Sian Iles, Stephanie M. Kaiser, Heather Frame, Steven Burrell, Angela M. Cheung, Can Assoc Radiol J., 2015 May;66(2):102-7. doi: 10.1016/j.carj.2014.01.002.Epub 2014 Jul 19
  22. Hypoparathyroidism: Current therapies for management – A Clinical Review, Hafsah Al- Azem and Aliya Khan, Best Practice and Research Clinical Endocrinology and Metabolism, 2012 Aug, 26(4):517-537
  23. Hyperparathyroidism – Diagnosis and Management – a Clinical Review, Shelley Pallan, Omair Rahman, Aliya Khan, British Medical Journal, 2012 Mar; 344:e1013
  24. Official Positions for FRAX® Bone Mineral Density and FRAX® simplification from Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX®,E. Michael Lewiecki, Juliet E. Compston, Paul D. Miller, Jonathon D. Adachi, Judith E. Adams, William D. Leslie, John A. Kanis, Alireza Moayyeri, Robert A. Adler, Didier B. Hans, David L. Kendler, Adolfo Diez-Perez, Marc-Antoine Kireg, Basel K. Masri, Roman R. Lorenc, Douglas C. Bauer, Glen M. Blake, Robert G. Josse, Patricia Clark, Aliya A. Khan, The International Society for Clinical Densitometry, Journal of Clinical Densitometry: Assessment of Skeletal Health, 2011;14(3):226-236
  25. Hypoparathyroidism in the Adult: Epidemiology, Diagnosis, Pathophysiology, Target-Organ Involvement, Treatment, and Challengers for Future Research, John P. Bilezikian, Aliya Khan, John T. Potts Jr., Maria Luisa Brandi, Bart L. Clarke, Dolores Shoback, Harald Juppner, Pierre D’Amour, John Fox, Lars Rejnmark, Leif Mosekilde, Mishaela R. Rubin,David Dempster, Rachel Gafni, Michael T. Collins, Jim Sliney, and James Sanders, JBMR 2011 Oct;26(10):2317-37. doi: 10.1002/jbmr.483
  26. Primary Hyperparathyroidism, Hafsah Al-Azem, Aliya Khan, CMAJ, 2011 Jul 12;183(10):E685-9. doi: 10.1503/cmaj.090675. Epub 2011 Apr 26
  27. Bisphosphonate-associated Osteonecrosis of the Jaw in Ontario: A Survey of Oral and Maxillofacial Surgeons, Aliya A. Khan, Lorena P. Rios, George K.B. Sandor, Nazir Khan,Edmund Peters, Mohammed O. Rahman, Cameron M.L. Clokie, Edward Dore and Sacha Dubois, Journal of Rheumatology, 2011 Jul;38(7):1396-402. doi: 10.3899/jrheum.100221. Epub 2011 Apr 15.Management of Hypoparathyroidism: Summary Statement and Guidelines, Maria Luisa Brandi, John P. Bilezikian, Dolores Shoback, Roger Bouillon, Bart Clarke, Rajesh V. Thakker, Aliya Khan, and John T. Potts Jr, JCEM Epub 2016 Mar, DOI: 10.1210/jc.2015-390
  28. Standards and Guidelines for Technologists Performing Central Dual-Energy X-Ray Absorptiometry by Aliya A. Khan, Anita Colquhoun, David A. Hanley Lawrence G. Jankowski, Robert G. Josse, , David L. Kendler, Brian Lentle, William D. Leslie, E. Michael Lewiecki, Elaine O’Neill, Stephen Robertson, Zeba A. Syed, S. Bobo Tanner and Dave Webster JCD, Vol.10, no.2, 189-195, 2007
  29. Management of Osteoporosis in men: an update and case example” Aliya A. Khan, Anthony B. Hodsman, Alexandra Papaioannou, David Kendler, Jacques P.  Brown, Wojciech P. OlszynksiCanadian Medical Association Journal, January 2007, 176(3), pp 345-348
  30. Standards for Performing DXA in Individuals with Secondary Causes of Osteoporosis from the Canadian Panel of International Society for Clinical DensitometryA.A. Khan, D.A. Hanley, J.P. Bilezikian, N. Binkley, J.P. Brown, A.B. Hodsman, R.G. Josse D.L Kendler, E.M. Lewiecki, P.D. Miller, W.P. Olszynski, S.M. Petak, Z.A Syed, D Theriault, N.B. Watts.JCD, Vol. 9, no. 1, 47-57, 2006
  31. “Management of Low Bone Mineral Density in Premenopausal Women” by Aliya Khan JOGC, April 2005, pp 345-349
  32. Alendronate in Primary Hyperparathyroidism: A Double-Blind, Randomized,Placebo-  Controlled Trial Khan AA, Bilezikian JP, Kung AWC, Ahmed MM, Dubois SJ, Ho AYY, Schussheim D,     Rubin MR, Shaikh AM, Silverberg SJ, Standish TI, Syed Z, Syed ZA, J Clin Endocrinol Metab, July 2004, 89(7):3319-3325.
  33. Position Statement: The Writing Group for the ISCD Position Development Conference by the Writing Group” (Aliya Khan) Diagnosis of osteoporosis in men, premenopausal women and children, JCD     Vol. 7, #1, 13-15, 2004.
  34. Standards and Guidelines for Performing Central Dual X-Ray Densitometry in Premenopausal Women, Men, and Children from the Canadian Panel of the International Society of Clinical Densitometry” Khan AA, Bachrach L, Brown JP, Hanley DA, Josse RG, Kendler DL, Leib ES, Lentle BC, Leslie WD, Lewiecki M, Miller PD, Nicholson RL, O’Brien C, Olszynski WP, Theriault MYD, Watts NB, JCD, Vol. 7, no. 1, 51-63, 2004.
  35. Position Paper:  Asymptomatic Primary Hyperparathyroidism – Standards and Guidelines for Diagnosis and Management in Canada Khan AA, Hanley DA, O’Brien CJ, Pasieka J, Ste-Marie LG, Rotstein LE, Rosen I, Young JEM, Josse RG, Bilezikian JP Endocrine Practice Vol. 9 No. 5 September/October 2003 pp 400-405.
  36. Standards and Guidelines for Performing Central Dual X-Ray Densitometry from      the Canadian Panel of             International Society for Clinical Densitometry By: Khan AA, Brown J, Faulkner K, Kendler D, Lentle B, Leslie W, Miller PD, Nicholson L, Olszynski WP and Watts NB, Journal of Clinical Densitometry Vol. 5, No. 4, 435-445, Winter 2002
  37. Standards and Guidelines for Performing Central Dual X-Ray Densitometry from the Canadian Panel of International Society for Clinical Densitometry By:  Khan AA, Brown J, Faulkner K, Kendler D, Lentle B, Leslie W, Miller P, Nicholson L, Olszynski WP, Watts NB Journal of Clinical Densitometry Vol 5. No. 3, 247-257, Fall 2002.
  38. The 2002 Canadian Bone Densitometry Recommendations: Take-home Messages By:Khan AA, Brown JP, Kendler DL, Leslie WD, Lentle BC, Lewiecki M, Miller PD, Nicholson RL, Olszynski WP, Watts NBCMAJ November 12, 2002; 167(10), 1141-1145.